Twilight Sparkle: <roll> Er, 15 Stealth? To peek through the door and listen without being caught?
DM: Cadenza?
Princess Cadance: She's fine. My Perception is worse than my Stealth. <ahem> I thought I made it perfectly clear I didn't want you to wear that.
Shining Armor: This crest was my favorite uncle's.
Princess Cadance: And?
Shining Armor: Aaaand I think I should wear it!
Twilight Sparkle: This... feels weird. This is weird, right?
DM: Spying on your brother and a Princess, looking for traces of evil?
Twilight Sparkle: No, I mean... Wathcing my actual brother and his actual fiancé _pretend_ to have a pre-marital squabble. *That's* the weird part.
DM: ...Well, when you put it like THAT...
Sometimes, an experimental combination of factors is so bizarre that you don't really know how it's going to go until you try it. Which... describes a lot of my campaigns, actually...
One seldom thinks how sometimes a player may not be weirded out by people being weird or disturbing in the game, but by people playing the game straight and innocent as can be and generating a dissonance due to tangential factors.
Not that one could or should do anything about it, the best you can do is roll with it.
I remember decades back in college I ran a super hero campaign and two of the players were roommates. There was an argument between the team on handling a super villain situation and the two players mentioned had an argument so convincing that I panicked thinking it was an OOC fight. But no, they assured us they were just acting. I was do convinced tho! I awarded a lot of exp that night.
I have a friend like that. Our characters can have a mean and insulting fight, and everyone thinks we're mad irl, but we're just having fun playing out a fight
Edit: In defense of the others, we play text-only, so it's much harder to tell what players are thinking
Goooooood. Feel that confusion swelling in you! Embrace the bewilderment! Give in to the anxiety and let it flow through you! Your rationalization and confirmation bias are no match for the power of the cognitive dissonance!